Active ingredientValsartanCat. No. P-V014-001CAS 137862-53-4
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Nitrosamine · Valsartan family
Pharmaceutical analytical standardN-Nitrosodiethylamine
Synonyms: N,N-diethylnitrous amide, Diethylnitrosamine, NDEA, Diethylnitrosoamine, N-Ethyl-N-nitrosoethanamine, N,N-Diethylnitrosoamine, Nitrosodiethylamine, N,N-Diethylnitrosamine, Diethylnitrosamide, DENA, Ethanamine, N-ethyl-N-nitroso-, Diethylamine, N-nitroso-, N-Nitroso-N,N-diethylamine, Diaethylnitrosamin, DEN (mutagen), N-Nitroso-diaethylamine, NSC 132, Nitrous diethylamide, DANA, Ethylamine, N-nitrosodi-, N-Diethylnitrosamine, Nitrosamine, diethyl-, Diethylnirtosamine, N-Nitrosodiethylamine (1mg/mL in Methanol), N-Nitrosodiethylamine 0.1 mg/ml in Methanol, N-Nitrosodiethylamine (100ug/mL in Methanol), Indapamide Impurity 40, Indapamide Impurity G, N-Nitroso-diethylamine CRS, N-Ethyl-N-nitroso-ethylamine, N-Nitrosodiethylamine, liquid, N-Nitroso-Diethylamine(Ndea), N-Nitrosodiethylamine, ISOPAC(R), N-Nitroso-diethylamine 100 microg/mL in Methanol, N-Nitroso-diethylamine 1000 microg/mL in Methanol
- Cat. No.
- P-V014-024
- CAS
- 55-18-5
- Alternative CAS
- N/A
- Formula
- C4H10N2O
- Molecular weight
- 102.14 g/mol
- Category
- Nitrosamine
Family: Valsartan
An angiotensin II receptor blocker (sartan) that relaxes blood vessels: patented in 1990 and in use since 1996 for high blood pressure, heart failure and after a heart attack.
Did you know?An amino acid hides in its molecule, valine: industrial synthesis starts from L-valine, onto which the biphenyl backbone typical of sartans is attached.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- N-NitrosodiethylamineEP Y0002258
More products in the Valsartan family
Active ingredientValsartanCat. No. P-V014-001CAS 137862-53-4
Pharmacopoeial impurityrac-Valsartan EP Impurity BCat. No. P-V014-002CAS 1894176-44-3
Pharmacopoeial impurityValsartan EP Impurity ACat. No. P-V014-003CAS 137862-87-4
Pharmacopoeial impurityValsartan EP Impurity BCat. No. P-V014-004CAS 137863-20-8
Pharmacopoeial impurityValsartan EP Impurity CCat. No. P-V014-005CAS 952652-79-8
Pharmacopoeial impurityValsartan USP Related Compound ECat. No. P-V014-006CAS 137863-17-3
Isotopically labelledrac-Valsartan-d9Cat. No. P-V014-008
Isotopically labelledValsartan-d3Cat. No. P-V014-010CAS 1331908-02-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.