Active ingredientImiquimodCat. No. P-I034-001CAS 99011-02-6
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Impurity or related compound · Imiquimod family
Pharmaceutical analytical standardN4-Isobutylquinoline-3,4-diamine Hydrochloride
Synonyms: 3-Amino-4-(isobutylamino)quinoline Hydrochloride, Imiquimod USP Related Compound E Hydrochloride
- Cat. No.
- P-I034-021
- CAS
- 935521-01-0
- Alternative CAS
- 99010-09-0 (free base)
- Formula
- C13H17N3·HCl
- Molecular weight
- 251.76 g/mol
- Category
- Impurity or related compound
Family: Imiquimod
An immune response modifier of the imidazoquinoline family, applied to the skin as a cream: approved in the United States in 1997 for genital warts, it is also used for actinic keratoses and some superficial basal cell carcinomas.
Did you know?It does not directly kill viruses or tumour cells: it activates the TLR7 receptor on immune cells, a target identified only in 2002, five years after approval.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Imiquimod family
Active ingredientImiquimodCat. No. P-I034-001CAS 99011-02-6
Pharmacopoeial impurityImiquimod USP Related Compound ACat. No. P-I034-002CAS 99010-24-9
Pharmacopoeial impurityImiquimod USP Related Compound BCat. No. P-I034-003CAS 99010-63-6
Pharmacopoeial impurityImiquimod USP Related Compound CCat. No. P-I034-004CAS 99010-64-7
Pharmacopoeial impurityImiquimod USP Related Compound DCat. No. P-I034-005CAS 853792-81-1
Isotopically labelled3-Hydroxy Imiquimod-d4Cat. No. P-I034-006
Isotopically labelledImiquimod Impurity 3-d6Cat. No. P-I034-007
Isotopically labelledImiquimod-d9Cat. No. P-I034-008CAS 2712126-48-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.