Active ingredientNadololCat. No. P-N003-002CAS 42200-33-9
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Pharmacopoeial impurity · Nadolol family
Pharmaceutical analytical standardNadolol EP Impurity E (Mixture of Diastereomers)
Synonyms: Nadolol EP Impurity E
- Cat. No.
- P-N003-006
- CAS
- 2434865-25-3
- Alternative CAS
- N/A
- Formula
- C17H26INO4
- Molecular weight
- 435.30 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Nadolol
A non-selective beta blocker patented in 1970 and in use since 1978: it is used for hypertension and angina pectoris and to prevent some arrhythmias.
Did you know?Unlike many beta blockers it is not processed by the liver: it leaves the body unchanged, in urine and faeces, and its half-life can reach about 24 hours.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nadolol family
Active ingredientNadololCat. No. P-N003-002CAS 42200-33-9
Pharmacopoeial impurityNadolol EP Impurity A (Mixture of Diastereomers)Cat. No. P-N003-003
Pharmacopoeial impurityNadolol EP Impurity D (Mixture of Diastereomers)Cat. No. P-N003-004
Pharmacopoeial impurityNadolol EP Impurity F HydrochlorideCat. No. P-N003-007CAS 15230-34-9
Pharmacopoeial impurityNadolol EP Impurity FCat. No. P-N003-008CAS 2116-22-5
Pharmacopoeial impurityNadolol EP Impurity G HydrochlorideCat. No. P-N003-009CAS 15148-92-2
Pharmacopoeial impurityNadolol EP Impurity GCat. No. P-N003-010CAS 33841-03-1
Isotopically labelledNadolol-d5Cat. No. P-N003-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.