Active ingredientNaphazoline HydrochlorideCat. No. P-N020-002CAS 550-99-2
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Active ingredient · Naphazoline family
Pharmaceutical analytical standardNaphazoline
Synonyms: 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole, Nafazolina, Clearine, Nafazolin, alpha-Naphthylmethyl imidazoline, Tele Stulln, AK Con, Vasoconstrictor Pensa, Pensa, Vasoconstrictor, Naphthizine, Antan, Naphcon, Nafazoline, Rhinazine, Imidin
- Cat. No.
- P-N020-001
- CAS
- 835-31-4
- Alternative CAS
- 5144-52-5 (nitrate)
- 550-99-2 (hydrochloride)
- 2918776-42-6 (dihydrochloride)
- 10061-11-7 (alternative CAS, same compound)
- Formula
- C14H14N2
- Molecular weight
- 210.28 g/mol
- Category
- Active ingredient (API)
A vasoconstrictor of the imidazoline family, patented in 1934 and used since the early 1940s as a nasal decongestant; today it is also found in eye drops for red eyes.
Did you know?Its name recalls the two parts of the molecule: naphthalene, the substance of old-fashioned mothballs, and the imidazoline ring that names its chemical family.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Naphazoline family
Active ingredientNaphazoline HydrochlorideCat. No. P-N020-002CAS 550-99-2
Active ingredientNaphazoline NitrateCat. No. P-N020-003CAS 5144-52-5
Pharmacopoeial impurityNaphazoline EP Impurity ACat. No. P-N020-004CAS 36321-43-4
Pharmacopoeial impurityNaphazoline EP Impurity BCat. No. P-N020-005CAS 86-87-3
Pharmacopoeial impurityNaphazoline EP Impurity CCat. No. P-N020-006CAS 132-75-2
Pharmacopoeial impurityNaphazoline EP Impurity DCat. No. P-N020-007CAS 22126-67-6
NitrosamineN-Nitroso NaphazolineCat. No. P-N020-010CAS 2703749-87-3
Impurity1,2-DiisothiocyanatoethaneCat. No. P-N020-011CAS 3688-08-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.