Active ingredientNevirapineCat. No. P-N043-001CAS 129618-40-2
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Impurity or related compound · Nevirapine family
Pharmaceutical analytical standardNevirapine Butenyl Analogue
- Cat. No.
- P-N043-018
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C18H18N4O
- Molecular weight
- 306.37 g/mol
- Category
- Impurity or related compound
Family: Nevirapine
The first non-nucleoside reverse transcriptase inhibitor, approved in 1996 against HIV-1: it binds directly to the virus's enzyme, blocking it, and in treatment it is used in combination with other antiretrovirals.
Did you know?A study carried out in Uganda and published in 1999 showed that a very simple treatment, given to the mother during labour and to the newborn, greatly reduced mother-to-child transmission of HIV.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nevirapine family
Active ingredientNevirapineCat. No. P-N043-001CAS 129618-40-2
Active ingredientNevirapine HemihydrateCat. No. P-N043-002CAS 220988-26-1
Pharmacopoeial impurityNevirapine EP Impurity ACat. No. P-N043-003CAS 133627-17-5
Pharmacopoeial impurityNevirapine EP Impurity BCat. No. P-N043-004CAS 287980-84-1
Pharmacopoeial impurityNevirapine EP Impurity CCat. No. P-N043-005CAS 287980-85-2
Isotopically labelledNevirapine-d4Cat. No. P-N043-006CAS 1051418-95-1
Isotopically labelledNevirapine-d5Cat. No. P-N043-007CAS 1189717-29-0
Impurity12-hydroxy NevirapineCat. No. P-N043-009CAS 133627-24-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.