Active ingredientNimesulideCat. No. P-N066-001CAS 51803-78-2
Drag to rotate
Pharmacopoeial impurity · Nimesulide family
Pharmaceutical analytical standardNimesulide EP Impurity G
Synonyms: 4-Nitro-2-phenoxyphenol, Nimesulide Impurity G, Phenol, 4-nitro-2-phenoxy-
- Cat. No.
- P-N066-008
- CAS
- 70995-08-3
- Alternative CAS
- N/A
- Formula
- C12H9NO4
- Molecular weight
- 231.21 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Nimesulide
A non-steroidal anti-inflammatory drug, a relatively selective COX-2 inhibitor, first marketed in Italy in 1985 and used as a painkiller and anti-inflammatory.
Did you know?Unlike most NSAIDs it is not a carboxylic acid: it is a sulfonanilide, with a nitro group and a phenoxy ring in its molecule.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nimesulide family
Active ingredientNimesulideCat. No. P-N066-001CAS 51803-78-2
Pharmacopoeial impurityNimesulide EP Impurity ACat. No. P-N066-002CAS 51765-56-1
Pharmacopoeial impurityNimesulide EP Impurity BCat. No. P-N066-003CAS 51765-51-6
Pharmacopoeial impurityNimesulide EP Impurity CCat. No. P-N066-004CAS 2688-84-8
Pharmacopoeial impurityNimesulide EP Impurity DCat. No. P-N066-005CAS 5422-92-4
Pharmacopoeial impurityNimesulide EP Impurity ECat. No. P-N066-006CAS 905858-63-1
Pharmacopoeial impurityNimesulide EP Impurity FCat. No. P-N066-007CAS 51765-72-1
Isotopically labelled4-Hydroxy nimesulide-d4Cat. No. P-N066-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.