Active ingredientNitazoxanideCat. No. P-N074-001CAS 55981-09-4
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Pharmacopoeial impurity · Nitazoxanide family
Pharmaceutical analytical standardNitazoxanide USP Related Compound B
Synonyms: Tizoxanide, 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide, Benzamide, 2-hydroxy-N-(5-nitro-2-thiazolyl)-, Desacetyl-nitazoxanide, NSC 697856, NTZdes, EETizoxanide, Nitazoxanide impurity 01, N-(5-nitro-2-thiazolyl) salicyl-amide
- Cat. No.
- P-N074-003
- CAS
- 173903-47-4
- Alternative CAS
- 2743442-59-1 (sodium salt)
- Formula
- C10H7N3O4S
- Molecular weight
- 265.24 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Nitazoxanide
An antiparasitic discovered in the 1980s at the Pasteur Institute by Jean-François Rossignol, used against intestinal infections caused by Cryptosporidium parvum and Giardia lamblia; in the body it is quickly converted into the active metabolite tizoxanide.
Did you know?It is the prototype of the thiazolides: early studies showed activity against tapeworms, and today it is also studied as an antiviral, for example against influenza A virus.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nitazoxanide family
Active ingredientNitazoxanideCat. No. P-N074-001CAS 55981-09-4
Pharmacopoeial impurityNitazoxanide USP Related Compound ACat. No. P-N074-002CAS 121-66-4
Isotopically labelledTizoxanide-d4Cat. No. P-N074-004CAS 1246817-56-0
ImpurityNitazoxanide Impurity 1Cat. No. P-N074-006CAS 952686-58-7
Impurity2-(Thiazol-2-ylcarbamoyl)phenyl acetateCat. No. P-N074-007CAS 402848-76-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.