Active ingredientOclacitinib MaleateCat. No. P-O003-002CAS 1208319-27-0
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Active ingredient · Oclacitinib family
Pharmaceutical analytical standardOclacitinib
Synonyms: JAKI, Apoquel, Apoquel (veterinary use), Cyclohexanemethanesulfonamide, n-methyl-4-(methyl-7h-pyrrolo(2,3-d)pyrimidin-4-ylamino)-, trans-, n-methyl(trans-4-(methyl(7h-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
- Cat. No.
- P-O003-001
- CAS
- 1208319-26-9
- Alternative CAS
- 1640292-55-2 (maleate)
- 1208319-27-0 (maleate)
- 1538596-97-2 (alternative CAS, same compound)
- Formula
- C15H23N5O2S
- Molecular weight
- 337.44 g/mol
- Category
- Active ingredient (API)
A Janus kinase inhibitor, mainly selective for JAK1, developed for dogs: approved in the United States in 2013, it controls itching from allergic dermatitis and atopic dermatitis.
Did you know?It works fast: in most dogs itching eases within about four hours and is gone within 24, because it dampens the signals of itch cytokines such as IL-31.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Oclacitinib family
Active ingredientOclacitinib MaleateCat. No. P-O003-002CAS 1208319-27-0
Isotopically labelledOclacitinib-13C-d3Cat. No. P-O003-003CAS 2750534-84-8
ImpurityOclacitinib Maleate cis-isomerCat. No. P-O003-004Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.