Active ingredientOfloxacinCat. No. P-O010-001CAS 82419-36-1
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Pharmacopoeial impurity · Ofloxacin family
Pharmaceutical analytical standardOfloxacin EP Impurity E
Synonyms: N-Desmethyl ofloxacin, Ofloxacin impurity e (ep impurity), Ofloxacin specified impurity E, Desmethyl-ofloxacin
- Cat. No.
- P-O010-006
- CAS
- 82419-52-1
- Alternative CAS
- 402930-70-5 (hydrochloride)
- 97791-27-0 (alternative CAS, same compound)
- Formula
- C17H18FN3O4
- Molecular weight
- 347.35 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Ofloxacin
A second-generation fluoroquinolone antibiotic, patented in 1980 and first approved in Japan in 1985, that blocks bacterial DNA gyrase and is used against many infections.
Did you know?It is a mixture of two mirror-image forms: the (S) form, separated later, became a drug in its own right, levofloxacin, on the market since 1993.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Ofloxacin impurity E CRSEP O0120050
More products in the Ofloxacin family
Active ingredientOfloxacinCat. No. P-O010-001CAS 82419-36-1
Pharmacopoeial impurityOfloxacin EP Impurity ACat. No. P-O010-002CAS 82419-35-0
Pharmacopoeial impurityOfloxacin EP Impurity BCat. No. P-O010-003CAS 123155-82-8
Pharmacopoeial impurityOfloxacin EP Impurity CCat. No. P-O010-004CAS 95848-94-5
Pharmacopoeial impurityOfloxacin EP Impurity DCat. No. P-O010-005CAS 197291-75-1
Pharmacopoeial impurityOfloxacin EP Impurity FCat. No. P-O010-007CAS 104721-52-0
Pharmacopoeial impurityOfloxacin EP Impurity F HydrochlorideCat. No. P-O010-008CAS 2731368-77-5
MetaboliteOfloxacin Acyl-beta-D-glucuronideCat. No. P-O010-009CAS 90293-81-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.