Active ingredientOmarigliptinCat. No. P-O020-001CAS 1226781-44-7
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Impurity or related compound · Omarigliptin family
Pharmaceutical analytical standardOmarigliptin Impurity D
Synonyms: tert-butyl N-[(2S,3S)-2-(2,5-difluorophenyl)-5-oxooxan-3-yl]carbamate, Omarigliptin Impurity 7, Tert-butyl ((2S,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate
- Cat. No.
- P-O020-008
- CAS
- 1456616-44-6
- Alternative CAS
- N/A
- Formula
- C16H19F2NO4
- Molecular weight
- 327.33 g/mol
- Category
- Impurity or related compound
Family: Omarigliptin
A DPP-4 inhibitor (gliptin) for type 2 diabetes, approved in Japan in 2015: unlike most gliptins, it has a very long duration of action.
Did you know?It was not the first gliptin of this kind: trelagliptin had preceded it in Japan by a few months. In 2016 its development for the United States and Europe was stopped for commercial reasons, not for safety or efficacy reasons.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Omarigliptin family
Active ingredientOmarigliptinCat. No. P-O020-001CAS 1226781-44-7
ImpurityOmarigliptin Impurity 1Cat. No. P-O020-002CAS 1211594-55-6
ImpurityOmarigliptin Impurity 2Cat. No. P-O020-003CAS 1588322-50-2
ImpurityOmarigliptin Impurity 3Cat. No. P-O020-004CAS 951127-31-4
ImpurityOmarigliptin Impurity ECat. No. P-O020-005CAS 1456616-43-5
ImpurityOmarigliptin Impurity 4Cat. No. P-O020-006CAS 951127-25-6
ImpurityOmarigliptin Impurity CCat. No. P-O020-007CAS 1456616-42-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.