Active ingredientOrphenadrineCat. No. P-O037-001CAS 83-98-7
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Pharmacopoeial impurity · Orphenadrine family
Pharmaceutical analytical standardOrphenadrine EP Impurity A
Synonyms: 2-Methylbenzhydrol, o-Methylbenzhydrol, NSC 27910, Benzenemethanol, 2-methyl-alpha-phenyl-, Phenyl(o-tolyl)methanol, Benzhydrol, 2-methyl-, Benzenemethanol, 2-methyl-a-phenyl-, o-tolyl(phenyl)methanol, Phenyl(2-tolyl)methanol, alpha-o-Tolylbenzyl alcohol, Cambridge id 5152776, Orphenadrine impurity a, alpha-(2-methylphenyl)benzenemethanol, alpha-(2-methylphenyl)benzyl alcohol
- Cat. No.
- P-O037-005
- CAS
- 5472-13-9
- Alternative CAS
- N/A
- Formula
- C14H14O
- Molecular weight
- 198.26 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Orphenadrine
An anticholinergic muscle relaxant used for pain from muscle strains and sprains and, in the past, for Parkinson's disease; a derivative of diphenhydramine, it was developed in the United States in the late 1940s.
Did you know?Its development was led by George Rieveschl, the same chemist who gave rise to diphenhydramine: the two molecules differ by a single methyl group added to one of the benzene rings.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Orphenadrine family
Active ingredientOrphenadrineCat. No. P-O037-001CAS 83-98-7
Active ingredientOrphenadrine CitrateCat. No. P-O037-002CAS 4682-36-4
Active ingredientOrphenadrine HydrochlorideCat. No. P-O037-003CAS 341-69-5
Pharmacopoeial impurityOrphenadrine EP Impurity ECat. No. P-O037-004CAS 21945-86-8
Pharmacopoeial impurityOrphenadrine EP Impurity BCat. No. P-O037-006CAS 131-58-8
Pharmacopoeial impurityOrphenadrine EP Impurity C HydrochlorideCat. No. P-O037-007CAS 17752-32-8
Pharmacopoeial impurityOrphenadrine EP Impurity DCat. No. P-O037-008CAS 58-73-1
Pharmacopoeial impurityOrphenadrine EP Impurity E HydrochlorideCat. No. P-O037-009CAS 17630-53-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.