Active ingredientOxaliplatinCat. No. P-O047-001CAS 61825-94-3
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Impurity or related compound · Oxaliplatin family
Pharmaceutical analytical standardOxaliplatin Impurity 1
Synonyms: trans-(+)-1,2-diaminocyclohexane
- Cat. No.
- P-O047-008
- CAS
- 111263-58-2
- Alternative CAS
- N/A
- Formula
- C8H16N2O6Pt
- Molecular weight
- 431.30 g/mol
- Category
- Impurity or related compound
Family: Oxaliplatin
A platinum-based anticancer drug developed in the 1970s in Japan by Yoshinori Kidani at Nagoya City University; approved in Europe in 1996 and in the United States in 2002, it is used mainly for colorectal cancer.
Did you know?Compared with cisplatin and carboplatin, the two amine groups bound to platinum are replaced by a single diaminocyclohexane ring, while an oxalate group completes the structure.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Oxaliplatin family
Active ingredientOxaliplatinCat. No. P-O047-001CAS 61825-94-3
Pharmacopoeial impurityOxaliplatin EP Impurity CCat. No. P-O047-003CAS 111321-67-6
Pharmacopoeial impurityOxaliplatin EP Impurity DCat. No. P-O047-004CAS 61758-77-8
Pharmacopoeial impurityOxaliplatin EP Impurity BCat. No. P-O047-005CAS 89955-85-1
Isotopically labelledOxaliplatin-d10Cat. No. P-O047-007
Pharmacopoeial impurityOxaliplatin EP Impurity E DinitrateCat. No. P-O047-009CAS 82398-34-3
Impurity(R,R)-Dichloro(1,2-diaminocyclohexane)platinum(II)Cat. No. P-O047-011CAS 61848-66-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.