Impurity3-Aminopropanoic AcidCat. No. P-P011-002CAS 107-95-9
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Active ingredient · Pamidronic Acid family
Pharmaceutical analytical standardPamidronic Acid
Synonyms: Pamidronate, Amidronate, Ribodroat, AHPrBP, Aminopropanehydroxydiphosphonate, Aminohydroxypropylidene Diphosphonate, Aredia, Phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, Bisphosphonate 6, Amidronic Acid, Propane-1-hydroxy-3-amino-1,1-diphosphonic acid, Phosphonic acid, P,P'-(3-amino-1-hydroxypropylidene)bis-, Dihydrogen (3-amino-1-hydroxypropylidene)diphosphonate
- Cat. No.
- P-P011-001
- CAS
- 40391-99-9
- Alternative CAS
- 109552-15-0 (sodium salt hydrate)
- 57248-88-1 (sodium salt)
- 1159812-33-5 (alternative CAS, same compound)
- 106437-12-1 (alternative CAS, same compound)
- Formula
- C3H11NO7P2
- Molecular weight
- 235.07 g/mol
- Category
- Active ingredient (API)
A nitrogen-containing bisphosphonate given by intravenous infusion: patented in 1971 and approved for medical use in 1987, it is used for high blood calcium, Paget's disease of bone and to protect bone in cancers such as multiple myeloma.
Did you know?It has also been used experimentally in osteogenesis imperfecta, the genetic condition known as 'brittle bone disease'.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pamidronic Acid family
Impurity3-Aminopropanoic AcidCat. No. P-P011-002CAS 107-95-9
Active ingredientDisodium PamidronateCat. No. P-P011-003CAS 57248-88-1
Active ingredientPamidronate disodium pentahydrateCat. No. P-P011-004CAS 109552-15-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.