Active ingredientParecoxib SodiumCat. No. P-P022-001CAS 198470-85-8
Drag to rotate
Impurity or related compound · Parecoxib family
Pharmaceutical analytical standardParecoxib
Synonyms: Valdecoxib Impurity J, Valdecoxib Impurity 38, N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide, Xapit, Rayzon, N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide, Propanamide, N-((4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)-, N-(((5-methyl-3-phenylisoxazol-4-yl)-phenyl)sulfonyl)propanamide, N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide, Parecoxib (USAN/INN), Parecoxib 100 microg/mL in Acetonitrile
- Cat. No.
- P-P022-051
- CAS
- 198470-84-7
- Alternative CAS
- N/A
- Formula
- C19H18N2O4S
- Molecular weight
- 370.42 g/mol
- Category
- Impurity or related compound
Family: Parecoxib
A selective COX-2 inhibitor anti-inflammatory given intravenously or intramuscularly, approved in Europe in 2002 for the short-term treatment of pain after surgery.
Did you know?It was the first selective COX-2 inhibitor that could be given by injection: a water-soluble prodrug that the liver converts into valdecoxib, the molecule that actually does the work.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Parecoxib family
Active ingredientParecoxib SodiumCat. No. P-P022-001CAS 198470-85-8
Isotopically labelledDiethyl sulfate-d10Cat. No. P-P022-003CAS 96617-81-1
ImpurityParecoxib Impurity 1Cat. No. P-P022-004CAS 2304623-35-4
Impurity2-PhenylacetophenoneCat. No. P-P022-005CAS 451-40-1
ImpurityParecoxib Impurity 2Cat. No. P-P022-006CAS 2338845-31-9
ImpurityParecoxib-001Cat. No. P-P022-007CAS 181696-73-1
Impurity5-methyl-3,4-diphenylisoxazoleCat. No. P-P022-008CAS 37928-17-9
ImpurityDiethyl SulfateCat. No. P-P022-009CAS 64-67-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.