Impurity or related compound · Pentamidine family
Pharmaceutical analytical standardPentamidine Diisetionate
Synonyms: Pentamidine Isethionate, Pentamidine diisethionate, Pentamidine isetionate, Pentacarinat, Nebupent, Lomidin, Pneumopent, Diamidine, Lomidine isoethionate, PENTAM, USAF XR-10, Pentamidini isetionas, NSC 620107, NSC 757400, p,p'-(Pentamethylenedioxy)dibenzamidine bis(beta-hydroxyethanesulfonate), Pentamidine isothionate, Lomidine, Pentaminide isetionate, Pentamidin-Isethionat, Pentamidine isetionate RS, Pentamidine diisetio, Pentamidine bis(2-hydroxyethanesulfonate), Benzamidine, 4,4'-(pentamethylenedioxy)di-, bis(beta-hydroxyethanesulfonate)
- Cat. No.
- P-P048-003
- CAS
- 140-64-7
- Alternative CAS
- 100-33-4 (free base)
- 112667-20-6 (mesylate)
- 50357-45-4 (dihydrochloride)
- 6823-79-6 (mesylate)
- Formula
- C19H24N4O2·2C2H6O4S
- Molecular weight
- 592.68 g/mol
- Category
- Impurity or related compound
Family: Pentamidine
An antimicrobial of the aromatic diamidine family, used since 1937 against African sleeping sickness and since 1940 against leishmaniasis; today it also treats and prevents Pneumocystis pneumonia and is on the WHO List of Essential Medicines.
Did you know?In the early 1980s an unusual rise in requests for pentamidine to the US CDC, to treat Pneumocystis pneumonia in young men, helped to reveal the emergence of AIDS.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pentamidine diisetionate CRSEP P0405000
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.