Active ingredientPentobarbital Sodium SaltCat. No. P-P053-002CAS 57-33-0
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Active ingredient · Pentobarbital family
Pharmaceutical analytical standardPentobarbital
Synonyms: 5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione, Pentobarbitone, Nembutal, Mebubarbital, Pentobarbituric acid, Ethaminal, Dorsital, Mebumal, Rivadorm, Pentobarbiturate, Pentabarbitone, Neodorm (new), Pentabarbital, NSC 28708, Barbituric acid, 5-ethyl-5-(1-methylbutyl)-, Aethaminalum, DEA No. 2270, Phetobarbitone, Ethyl-propylmethylcarbinylbarbituric acid, Barbituric acid, 5-ethyl-5-(2-pentyl)-, Pharmakon1600-01900006, NSC 760434
- Cat. No.
- P-P053-001
- CAS
- 76-74-4
- Alternative CAS
- 57-33-0 (sodium salt)
- 24876-35-5 (calcium salt)
- 3330-47-0 (calcium salt)
- 7563-42-0 (calcium salt)
- Formula
- C11H18N2O3
- Molecular weight
- 226.28 g/mol
- Category
- Active ingredient (API)
A barbiturate developed in 1930 by chemists Ernest Volwiler and Donalee Tabern, used as a sedative, before anaesthesia, to control emergency seizures and to lower intracranial pressure; in veterinary medicine it is used as an anaesthetic.
Did you know?The same two chemists synthesised thiopental, a famous intravenous anaesthetic, in 1934, and for this they were inducted into the US National Inventors Hall of Fame in 1986.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pentobarbital CRSEP P0500000
More products in the Pentobarbital family
Active ingredientPentobarbital Sodium SaltCat. No. P-P053-002CAS 57-33-0
Pharmacopoeial impurityPentobarbital EP Impurity ECat. No. P-P053-003CAS 17013-37-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.