Active ingredientPentoxyverine CitrateCat. No. P-P055-001CAS 23142-01-0
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Pharmacopoeial impurity · Pentoxyverine family
Pharmaceutical analytical standardPentoxyverine EP Impurity B
Synonyms: Caramiphen, 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate, Caramiphene, Caramiphenum, Caramifeno, Parpanil, Pentaphen (pharmaceutical), Cyclopentanecarboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester, Caramifenio, Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate, Caramiphen (free base)
- Cat. No.
- P-P055-002
- CAS
- 77-22-5
- Alternative CAS
- 125-85-9 (hydrochloride)
- Formula
- C18H27NO2
- Molecular weight
- 289.42 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Pentoxyverine
A centrally acting cough suppressant, also known as carbetapentane, patented in the mid-1950s by the chemist H. G. Morren; it is used for dry cough due to colds, bronchitis and sinusitis.
Did you know?Besides calming cough it binds strongly to sigma-1 receptors in the nervous system and also has antispasmodic and local anaesthetic properties.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pentoxyverine impurity B CRSEP Y0000099
More products in the Pentoxyverine family
Active ingredientPentoxyverine CitrateCat. No. P-P055-001CAS 23142-01-0
Pharmacopoeial impurityPentoxyverine EP Impurity ACat. No. P-P055-003CAS 77-55-4
Impurity1-PhenylcyclopentanecarbonitrileCat. No. P-P055-006CAS 77-57-6
Impurity1-PhenylcyclopentanecarboxamideCat. No. P-P055-007CAS 5296-89-9
Impurity6-Hydroxy-2-phenylhexanenitrileCat. No. P-P055-008CAS 105539-06-8
ImpurityPentoxyverine Impurity 1Cat. No. P-P055-010
ImpurityPentoxyverine Impurity 2Cat. No. P-P055-011
ImpurityPentoxyverine Impurity 3Cat. No. P-P055-012Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.