Active ingredientPhenoxymethylpenicillin PotassiumCat. No. P-P083-001CAS 132-98-9
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Pharmacopoeial impurity · Phenoxymethylpenicillin family
Pharmaceutical analytical standardPhenoxymethylpenicillin EP Impurity E
Synonyms: Penicilloic V Acid, Penicilloic acid V, NSC 74505, NSC 163496, Phenoxomethylpenicilloyl
- Cat. No.
- P-P083-005
- CAS
- 1049-84-9
- Alternative CAS
- 1049-83-8 (alternative CAS, same compound)
- Formula
- C16H20N2O6S
- Molecular weight
- 368.40 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Phenoxymethylpenicillin
Penicillin V, stable in stomach acid and therefore suitable to be taken by mouth: first obtained in 1948 in the United States without its value being understood, it was rediscovered and developed in 1951 in Kundl, in the Tyrol, by the biologist Ernst Brandl.
Did you know?Brandl obtained it almost by chance, by adding a disinfectant, phenoxyethanol, to the fermentation tanks to fight contamination; the 'V' reportedly stands for vertraulich, German for 'confidential'.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Phenoxymethylpenicillin family
Active ingredientPhenoxymethylpenicillin PotassiumCat. No. P-P083-001CAS 132-98-9
Pharmacopoeial impurityPhenoxymethylpenicillin EP Impurity BCat. No. P-P083-002CAS 122-59-8
Pharmacopoeial impurityPhenoxymethylpenicillin EP Impurity DCat. No. P-P083-003CAS 20880-67-5
Pharmacopoeial impurityPhenoxymethylpenicillin EP Impurity E HClCat. No. P-P083-006
Pharmacopoeial impurityPhenoxymethylpenicillin EP Impurity FCat. No. P-P083-008CAS 4847-29-4
Isotopically labelledPenicillin V-d5Cat. No. P-P083-009CAS 1356837-87-0
NitrosamineN-Nitroso Phenoxymethylpenicillin EP Impurity ECat. No. P-P083-010
NitrosamineN-Nitroso Phenoxymethylpenicillin EP Impurity FCat. No. P-P083-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.