Active ingredientPhytomenadioneCat. No. P-P104-001CAS 84-80-0
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Impurity or related compound · Phytomenadione family
Pharmaceutical analytical standardPhyllohydroquinone 1-Acetate
Synonyms: Vitamin K1 (Phytonadione) Related Compound 5, Vitamin K1 Impurity 35, Vitamin K1 Impurity 177
- Cat. No.
- P-P104-025
- CAS
- 50281-47-5
- Alternative CAS
- N/A
- Formula
- C33H50O3
- Molecular weight
- 494.76 g/mol
- Category
- Impurity or related compound
Family: Phytomenadione
Vitamin K1 from green plants, essential for blood clotting: isolated in 1939, it earned Henrik Dam and Edward Doisy the 1943 Nobel Prize. As a medicine it prevents vitamin K deficiency bleeding in newborns and counteracts excess anticoagulants.
Did you know?In leaves it works in photosynthesis as an electron acceptor: that is why it is so abundant in green leafy vegetables.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Phytomenadione family
Active ingredientPhytomenadioneCat. No. P-P104-001CAS 84-80-0
Pharmacopoeial impurityPhytomenadione EP Impurity ACat. No. P-P104-002CAS 58-27-5
Metabolite(2S,3R)-Epoxide Vitamin K1Cat. No. P-P104-003CAS 85954-59-2
Isotopically labelledcis-Vitamin K1-d7Cat. No. P-P104-004
Isotopically labelledVitamin K-d7Cat. No. P-P104-006CAS 1233937-39-7
Isotopically labelledVitamin K1-d7Cat. No. P-P104-007CAS 1373049-34-3
Impurity(2R,3S)-Epoxide Vitamin K1Cat. No. P-P104-008CAS 85955-78-8
ImpurityPhytomenadione Impurity 1Cat. No. P-P104-009CAS 562836-92-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.