Active ingredientPilocarpine NitrateCat. No. P-P110-002CAS 148-72-1
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Active ingredient · Pilocarpine family
Pharmaceutical analytical standardPilocarpine HCl
Synonyms: Pilocarpine Hydrochloride, Salagen, Sno pilo, Isopto carpine, Vistacarpin N, Pilopine hs, Pilopine, QLOSI, VUITY, Pilocarpinum muriaticum, Pilogel, Piloc hcl, Almocarpine, Pilocarpal, Pilocar, Pilocar SMP, Adsorbocarpine, Pilomiotin, Pilocel, Mistura P, Epicar, MI-Pilo Ophth Sol, Amistura P, Ami-pilo, Pilopine HS Gel, Mi-Pilo, Component of Epicar, Sanpilo, Component of Pilocar, PILO
- Cat. No.
- P-P110-001
- CAS
- 54-71-7
- Alternative CAS
- 92-13-7 (free base)
- 102282-25-7 (free base)
- 148-72-1 (nitrate)
- Formula
- C11H16N2O2·HCl
- Molecular weight
- 244.72 g/mol
- Category
- Active ingredient (API)
An alkaloid extracted from the leaves of jaborandi (Pilocarpus), a South American shrub: it has been used in glaucoma eye drops for over a century and today also to relieve dry mouth.
Did you know?It is the substance used in the sweat test for diagnosing cystic fibrosis: applied to the skin with a weak electric current (iontophoresis), it stimulates the sweat to be analysed.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pilocarpine hydrochloride CRSEP P1650000
More products in the Pilocarpine family
Active ingredientPilocarpine NitrateCat. No. P-P110-002CAS 148-72-1
Pharmacopoeial impurityPilocarpine EP Impurity A HClCat. No. P-P110-003CAS 28958-85-2
Pharmacopoeial impurityPilocarpine EP Impurity B Sodium Salt (Mixture of Diastereomers)Cat. No. P-P110-004CAS 2700080-55-1
Pharmacopoeial impurityPilocarpine EP Impurity B Sodium SaltCat. No. P-P110-005CAS 92598-79-3
Pharmacopoeial impurityPilocarpine EP Impurity C Sodium SaltCat. No. P-P110-006CAS 101769-87-3
Isotopically labelledPilocarpine EP Impurity B-d3 Sodium Salt (Mixture of Diastereomers)Cat. No. P-P110-007
Isotopically labelledPilocarpine-d3 HydrochlorideCat. No. P-P110-008CAS 1217838-88-4
ImpurityPilocarpine Impurity 1Cat. No. P-P110-009CAS 54467-57-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.