Active ingredientPimavanserinCat. No. P-P112-001CAS 706779-91-1
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Stable isotope labelled · Pimavanserin family
Pharmaceutical analytical standardPimavanserin-d4
- Cat. No.
- P-P112-005
- CAS
- N/A
- Alternative CAS
- 706779-91-1 (unlabelled form)
- 706782-28-7 (unlabelled form, tartrate)
- Formula
- C25H30D4FN3O2
- Molecular weight
- 431.59 g/mol
- Category
- Stable isotope labelled
Family: Pimavanserin
A medicine acting on serotonin 5-HT2A receptors, approved in the United States in April 2016 as the first treatment for the hallucinations and delusions of psychosis associated with Parkinson's disease.
Did you know?It is an inverse agonist: besides stopping serotonin from activating the 5-HT2A receptor, it also lowers the receptor's spontaneous activity, the activity it shows even without its messenger.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pimavanserin family
Active ingredientPimavanserinCat. No. P-P112-001CAS 706779-91-1
Active ingredientPimavanserin TartrateCat. No. P-P112-003CAS 706782-28-7
NitrosamineN-Nitroso Pimavanserin Impurity 1Cat. No. P-P112-006
ImpurityPimavanserin Impurity 1Cat. No. P-P112-007CAS 2518374-84-8
ImpurityPimavanserin Impurity 2Cat. No. P-P112-008CAS 1388858-78-3
ImpurityPimavanserin Impurity 3Cat. No. P-P112-009CAS 1399883-72-7
Impurity1-(Chloromethyl)-4-isobutoxybenzeneCat. No. P-P112-010CAS 40141-14-8
ImpurityPimavanserin Impurity 4Cat. No. P-P112-011CAS 639863-75-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.