Pharmacopoeial impurity · Piracetam family
Pharmaceutical analytical standardPiracetam EP Impurity A
Synonyms: Povidone EP Impurity B, 2-Pyrrolidone, pyrrolidin-2-one, Pyrrolidone, Butyrolactam, Pyrrolidon, gamma-Butyrolactam, alpha-Pyrrolidinone, gamma-Aminobutyric lactam, gamma-Aminobutyrolactam, alpha-Pyrrolidone, gamma-Aminobutyric acid lactam, Butanoic acid, 4-amino-, lactam, NSC 4593, NSC 8413, FEMA NO. 4829, MELAO Tea TreeShampoo, Pyrrolidinone, Pyrrolidone-2, Butanoic acid, lactam, Butyrolactim, Pyrollidone, a-pyrrolidone, Aminobutyrolactam, Soluphor P, Tetrahydropyrrolone, Aminobutyric lactam, Aminobutyric acid lactam, Pyrrolidin-2-one (2-Pyrrolidone), Pyrrolidin-2-one (1-aza-2-cyclopentanone)
- Cat. No.
- P-P129-002
- CAS
- 616-45-5
- Alternative CAS
- 63886-26-0 (hydrochloride)
- 24968-97-6 (alternative CAS, same compound)
- Formula
- C4H7NO
- Molecular weight
- 85.11 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Piracetam
A cyclic derivative of GABA synthesised in 1964 by the Romanian psychologist and chemist Corneliu Giurgea, who was studying analogues of this neurotransmitter in the 1960s. In Europe it is approved for myoclonus, sudden involuntary muscle jerks.
Did you know?To describe its effects, Giurgea coined the term nootropic in 1972, from the Greek words for mind and to turn.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pyrrolidone CRSEP Y0000659
More products in the Piracetam family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
