Active ingredientPirfenidoneCat. No. P-P134-001CAS 53179-13-8
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Stable isotope labelled · Pirfenidone family
Pharmaceutical analytical standardPirfenidone-d5
Synonyms: 5-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)pyridin-2-one, Pirfenidone-d5 (5-Methyl-N-Phenyl-2-1H-Pyridone-d5)
- Cat. No.
- P-P134-007
- CAS
- 1020719-62-3
- Alternative CAS
- 53179-13-8 (unlabelled form)
- Formula
- C12H6D5NO
- Molecular weight
- 190.26 g/mol
- Category
- Stable isotope labelled
Family: Pirfenidone
An oral antifibrotic for idiopathic pulmonary fibrosis, a disease in which the lung stiffens through excess scar tissue: first approved in Japan in 2008 and in Europe in 2011.
Did you know?In the 1970s it was described as an anti-inflammatory; only in the 1990s was it found to curb collagen production and fibroblast growth in the lungs of laboratory animals.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pirfenidone family
Active ingredientPirfenidoneCat. No. P-P134-001CAS 53179-13-8
Pharmacopoeial impurityPirfenidone EP Impurity BCat. No. P-P134-002CAS 1003-68-5
Metabolite5-Carboxy-pirfenidone acyl glucuronideCat. No. P-P134-003
Metabolite5-Hydroxymethyl-pirfenidone O glucuronideCat. No. P-P134-004
Isotopically labelled4'-Hydroxy-pirfenidone-d4Cat. No. P-P134-005CAS 1188263-50-4
Isotopically labelled5-Carboxy-pirfenidone-d5Cat. No. P-P134-006CAS 1020719-24-7
Nitrosamine5-Methyl-N-nitroso-2-pyridinamineCat. No. P-P134-008CAS 126209-21-0
Nitrosamine3-Methyl-1-nitrosopyridin-2-oneCat. No. P-P134-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.