Active ingredientPodophyllotoxinCat. No. P-P149-001CAS 518-28-5
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Impurity or related compound · Podophyllotoxin family
Pharmaceutical analytical standardPodophyllotoxin 4-O-Glucoside
Synonyms: Podophyllotoxin Impurity 8, Podophyllotoxin glucoside, SP-G Iia, Podophyllotoxin beta-D-glucoside, NSC 163024, Podophyllotoxin, 3-beta-D-glucopyranoside, Podophyllotoxin, beta-D-glucopyranoside
- Cat. No.
- P-P149-009
- CAS
- 16481-54-2
- Alternative CAS
- N/A
- Formula
- C28H32O13
- Molecular weight
- 576.55 g/mol
- Category
- Impurity or related compound
Family: Podophyllotoxin
A lignan extracted from the rhizomes of the mayapple (Podophyllum peltatum), a plant of North American woodlands already used by Native Americans: it blocks cell division and is applied to the skin to treat genital warts.
Did you know?The name Podophyllum combines the Greek words for 'foot' and 'leaf', because the leaf resembles a duck's webbed foot; the anticancer drugs etoposide and teniposide derive from this molecule.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Podophyllotoxin family
Active ingredientPodophyllotoxinCat. No. P-P149-001CAS 518-28-5
Pharmacopoeial impurityPodophyllotoxin EP Impurity CCat. No. P-P149-002CAS 477-49-6
Isotopically labelledPodophyllotoxin-d9Cat. No. P-P149-003
Impurity6,7-DemethylenedeoxypodophyllotoxinCat. No. P-P149-004CAS 1173-42-8
ImpurityDeoxypodophyllotoxinCat. No. P-P149-006CAS 19186-35-7
ImpurityEpipodophyllotoxinCat. No. P-P149-007CAS 4375-07-9
Pharmacopoeial impurityPodophyllotoxin EP Impurity ACat. No. P-P149-008CAS 477-47-4
ImpurityPodophyllotoxin Impurity 1Cat. No. P-P149-011CAS 3590-88-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.