Active ingredientPramipexoleCat. No. P-P164-001CAS 104632-26-0
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Impurity or related compound · Pramipexole family
Pharmaceutical analytical standardPramipexole Impurity 22
Synonyms: N-[(6S)-2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-N-propylhydroxylamine
- Cat. No.
- P-P164-059
- CAS
- 1965329-42-3
- Alternative CAS
- N/A
- Formula
- C10H17N3OS
- Molecular weight
- 227.33 g/mol
- Category
- Impurity or related compound
Family: Pramipexole
A non-ergoline dopamine agonist: it stimulates brain receptors for dopamine, the neurotransmitter that runs short in Parkinson's disease. Approved in the United States in 1997, it is also used for restless legs syndrome.
Did you know?Its mirror image, dexpramipexole, has almost no dopamine activity but lowers eosinophils in the blood: for this reason it has been studied for eosinophilic asthma.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pramipexole family
Active ingredientPramipexoleCat. No. P-P164-001CAS 104632-26-0
Active ingredientPramipexole DihydrochlorideCat. No. P-P164-002CAS 104632-25-9
Active ingredientPramipexole Dihydrochloride MonohydrateCat. No. P-P164-003CAS 191217-81-9
Pharmacopoeial impurityPramipexole EP Impurity D DihydrochlorideCat. No. P-P164-004CAS 104632-27-1
Pharmacopoeial impurityPramipexole BP Impurity BCat. No. P-P164-005CAS 1246815-83-7
Pharmacopoeial impurityPramipexole EP Impurity A (as Racemate)Cat. No. P-P164-006CAS 104617-49-4
Pharmacopoeial impurityPramipexole EP Impurity ACat. No. P-P164-007CAS 106092-09-5
Pharmacopoeial impurityPramipexole EP Impurity B DihydrochlorideCat. No. P-P164-008CAS 1802051-36-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.