Active ingredientPramoxineCat. No. P-P167-001CAS 140-65-8
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Active ingredient · Pramoxine family
Pharmaceutical analytical standardPramoxine HCl
Synonyms: Pramoxine Hydrochloride, Tronothane, Walgreen Anti-Itch, CVS Health Maximum Strength Feminine, Curasore, Reeses, Dermal-Soothe, Proctofoam NS, Suffusion P, Honey Pot, Ivy Wash, Poison Ivy Wash, Deter-X, Comfort Conditioner, Pramox Creme rinse, Anti-Itch Soothing, Licefreee AfterLice, Cocoskin, VetraSeb CeraDerm P, Suffusion P MOUSSE, Leader Poison Ivy Wash, Reeses Pinworm Itch Relief, CVS Itch relief moisturizing, VetraSeb CeraDerm P MOUSSE, Cvs Fragrance Free Anti-itch, Sally Hansen Zero bump bikini, First Aid Sensitive Anti-Itch, Private Label Poison Ivy Wash, Prosoria Anti-Itch Moisturizer, DerMend Moisturizing Anti-Itch, LOLA Vaginal Itch Relief Wipes, CeraSoothe P ANTI-ITCH MOUSSE, First Degree Maximum Strength Burn, Aveeno Calm Plus Restore Itch Relief Balm, Strawfield pets anti-itch medicated, Cvs Pharmacy Maximum Strength Feminine Wipes, Aveeno Restorative Skin Therapy Itch Relief Balm, Vagisil Anti-itch Medicated Wipes Maximum Strength, Prax Lotion, Pramocaine HCl, Tronolane, Derma, Anti-Itch Wipe
- Cat. No.
- P-P167-002
- CAS
- 637-58-1
- Alternative CAS
- 140-65-8 (free base)
- Formula
- C17H27NO3·HCl
- Molecular weight
- 329.86 g/mol
- Category
- Active ingredient (API)
Family: Pramoxine
A topical local anaesthetic, also known as pramocaine, discovered in 1953 and used in creams and lotions for itching, sunburn, minor burns, insect bites and haemorrhoids.
Did you know?It differs from almost all other local anaesthetics: it is neither an amide nor an ester but carries a morpholine ring, and it has a low sensitising potential on the skin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pramoxine family
Active ingredientPramoxineCat. No. P-P167-001CAS 140-65-8
Impurity1,4-DibutoxybenzeneCat. No. P-P167-004CAS 104-36-9
Impurity4-ButoxyphenolCat. No. P-P167-005CAS 122-94-1
ImpurityPramoxine Impurity 1Cat. No. P-P167-006
ImpurityPramoxine Impurity DCat. No. P-P167-007CAS 2749415-65-2
ImpurityPramoxine N-OxideCat. No. P-P167-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.