Active ingredientPrednisoloneCat. No. P-P177-001CAS 50-24-8
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Impurity or related compound · Prednisolone family
Pharmaceutical analytical standardPrednisolone Impurity 8
Synonyms: Prednisolone-(E)-enolaldehyde
- Cat. No.
- P-P177-069
- CAS
- 118864-88-3
- Alternative CAS
- N/A
- Formula
- C21H26O4
- Molecular weight
- 342.43 g/mol
- Category
- Impurity or related compound
Family: Prednisolone
A synthetic glucocorticoid introduced in 1955 together with prednisone: it is a potent anti-inflammatory that retains less salt than cortisol, and is used in asthma, allergies, rheumatic and autoimmune diseases.
Did you know?It owes its existence to a bacterium: chemist Arthur Nobile discovered that Corynebacterium simplex turns cortisol (hydrocortisone) into prednisolone by adding a double bond to the molecule.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Prednisolone family
Active ingredientPrednisoloneCat. No. P-P177-001CAS 50-24-8
Active ingredientPrednisolone 17-AcetateCat. No. P-P177-002CAS 52628-64-5
Active ingredientPrednisolone 21-FormateCat. No. P-P177-003CAS 2141-22-2
Active ingredientPrednisolone AcetateCat. No. P-P177-004CAS 52-21-1
Active ingredientPrednisolone PhosphateCat. No. P-P177-006CAS 302-25-0
Active ingredientPrednisolone Sodium PhosphateCat. No. P-P177-007CAS 125-02-0
Active ingredientPrednisolone Succinate Sodium SaltCat. No. P-P177-008CAS 1715-33-9
Pharmacopoeial impurityMethylprednisolone EP Impurity DCat. No. P-P177-011CAS 1338549-02-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.