Active ingredientPretomanidCat. No. P-P184-001CAS 187235-37-6
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Impurity or related compound · Pretomanid family
Pharmaceutical analytical standardPretomanid Impurity 3
- Cat. No.
- P-P184-006
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C11H15N3O5
- Molecular weight
- 269.26 g/mol
- Category
- Impurity or related compound
Family: Pretomanid
An anti-tuberculosis drug of the nitroimidazole class, known during development as PA-824, approved in the United States in 2019 for highly drug-resistant pulmonary tuberculosis, together with bedaquiline and linezolid.
Did you know?It was chosen in 2000 from a series of about 100 nitroimidazole derivatives: it was not the most potent in the test tube, but it was the most active in infected mice when given by mouth.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pretomanid family
Active ingredientPretomanidCat. No. P-P184-001CAS 187235-37-6
Isotopically labelledPretomanid-d4Cat. No. P-P184-002CAS 1346617-34-2
ImpurityPretomanid 3-Nitro IsomerCat. No. P-P184-003CAS 1131004-99-3
ImpurityPretomanid Impurity 1Cat. No. P-P184-004
ImpurityPretomanid Impurity 2Cat. No. P-P184-005CAS 2222639-62-3
ImpurityPretomanid Impurity 4Cat. No. P-P184-007
ImpurityPretomanid Meta Isomer ImpurityCat. No. P-P184-008CAS 1353753-57-7
ImpurityPretomanid Methoxy ImpurityCat. No. P-P184-009CAS 2512206-85-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.