Active ingredientPrimaquine DiphosphateCat. No. P-P189-001CAS 63-45-6
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Impurity or related compound · Primaquine family
Pharmaceutical analytical standardPrimaquine Related Compound A
Synonyms: Quinocide, 1-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine, Chinocide, Quinocida, Quinocidum, NSC 50986, Quinoline, 8-((4-aminopentyl)amino)-6-methoxy-, N*1*-(6-Methoxy-quinolin-8-yl)-pentane-1,4-diamine, N-(4-aminopentyl)-N-(6-methoxy-8-quinolinyl)amine
- Cat. No.
- P-P189-024
- CAS
- 525-61-1
- Alternative CAS
- 1177093-23-0 (phosphate)
- 64992-36-5 (phosphate)
- 51050-49-8 (dihydrochloride)
- 69417-85-2 (hydrochloride)
- Formula
- C15H21N3O
- Molecular weight
- 259.35 g/mol
- Category
- Impurity or related compound
Family: Primaquine
An 8-aminoquinoline antimalarial, synthesised in 1946 by Robert Elderfield at Columbia University: it clears the dormant liver forms of Plasmodium vivax and Plasmodium ovale, preventing relapses.
Did you know?A single low dose also kills the gametocytes of Plasmodium falciparum, the parasite forms that pass to the mosquito: this is why the WHO recommends it to reduce malaria transmission.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Primaquine family
Active ingredientPrimaquine DiphosphateCat. No. P-P189-001CAS 63-45-6
Pharmacopoeial impurityPrimaquine EP Impurity BCat. No. P-P189-002CAS 85-81-4
Pharmacopoeial impurityPrimaquine EP Impurity CCat. No. P-P189-003CAS 90-52-8
Pharmacopoeial impurityPrimaquine EP Impurity DCat. No. P-P189-004CAS 83532-78-9
Isotopically labelledPrimaquine-13C-d3 DiphosphateCat. No. P-P189-005
Isotopically labelledPrimaquine-d3Cat. No. P-P189-006CAS 1318852-20-8
NitrosamineN-Nitroso Primaquine DiHClCat. No. P-P189-007
ImpurityPrimaquine Impurity 1Cat. No. P-P189-008CAS 84885-43-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.