Pharmacopoeial impurityPyridostigmine EP Impurity BCat. No. P-P238-002CAS 4685-07-8
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Active ingredient · Pyridostigmine family
Pharmaceutical analytical standardPyridostigmine Bromide
Synonyms: Kalimin, Kalymin, Regonol, Regonal, Mestinon bromide, Pyridostigmini bromidum, Piridostigmina bromuro, Pyridinium, 3-(((dimethylamino)carbonyl)oxy)-1-methyl-, bromide, Pyridinium, 3-hydroxyl-1-methyl-, bromide, dimethylcarbamate, Mestinon ret, Pryidostigmine Bromide, Pyridostigminii bromidum, Mestinon, Dimethylcarbamic acid ester of 3-hydroxy-1-methylpyridinium bromide, N,N-dimethyl(1-methyl(3-pyridyloxy))carboxamide, bromide, N,N-dimethylcarbamic acid (1-methylpyridin-1-ium-3-yl) ester bromide
- Cat. No.
- P-P238-001
- CAS
- 101-26-8
- Alternative CAS
- N/A
- Formula
- C9H13N2O2·Br
- Molecular weight
- 261.12 g/mol
- Category
- Active ingredient (API)
An acetylcholinesterase inhibitor patented in 1945 and in medical use since 1955, used mainly for the muscle weakness of myasthenia gravis and sometimes also for orthostatic hypotension.
Did you know?Like its predecessor neostigmine it is a carbamate with a permanently charged nitrogen, which stops it crossing the blood-brain barrier; it is on the WHO List of Essential Medicines.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pyridostigmine BromideBP 1033
- Pyridostigmine bromide CRSEP P4099900
More products in the Pyridostigmine family
Pharmacopoeial impurityPyridostigmine EP Impurity BCat. No. P-P238-002CAS 4685-07-8
Pharmacopoeial impurityPyridostigmine Bromide EP Impurity ACat. No. P-P238-003CAS 51581-32-9
Pharmacopoeial impurityPyridostigmine Bromide EP Impurity BCat. No. P-P238-004CAS 31034-86-3
Isotopically labelledPyridostigmine-d3 BromideCat. No. P-P238-005CAS 1633751-00-4
Isotopically labelledPyridostigmine-d6 BromideCat. No. P-P238-006CAS 2375858-08-3
Impurity3-Hydroxy-1-methyl-pyridinium IodideCat. No. P-P238-007CAS 7500-05-2
Impurity3-HydroxypyridineCat. No. P-P238-008CAS 109-00-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.