Isotopically labelledRacemic Ramosetron-d3 HClCat. No. P-R012-002
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Impurity or related compound · Ramosetron family
Pharmaceutical analytical standardRamosetron Impurity 6 Hydrochloride
Synonyms: Pyrrolidin-1-yl(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone hydrochloride
- Cat. No.
- P-R012-015
- CAS
- 132036-42-1
- Alternative CAS
- 788124-61-8 (free base)
- Formula
- C12H17N3O·HCl
- Molecular weight
- 255.75 g/mol
- Category
- Impurity or related compound
Family: Ramosetron
A serotonin 5-HT3 receptor antagonist launched in Japan in 1996 for chemotherapy-induced nausea and vomiting, and later also for irritable bowel syndrome with diarrhoea; it is used mainly in Asia.
Did you know?The suffix -setron unites the 5-HT3 antagonists, such as ondansetron and granisetron; ramosetron is one of the few in the family also used for irritable bowel syndrome with diarrhoea.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ramosetron family
Isotopically labelledRacemic Ramosetron-d3 HClCat. No. P-R012-002
Impurity(S)-RamosetronCat. No. P-R012-003CAS 132036-90-9
Impurity(S)-Ramosetron HClCat. No. P-R012-004CAS 137887-27-5
Impurity1-methyl-1H-indoleCat. No. P-R012-005CAS 603-76-9
Impurity1-Methylindole-3-carboxylic acidCat. No. P-R012-006CAS 32387-21-6
Impurity1-methylindoline-2,3-dioneCat. No. P-R012-007CAS 2058-74-4
ImpurityRamosetron Impurity 1Cat. No. P-R012-008CAS 1352491-75-8
ImpurityRamosetron Impurity 2Cat. No. P-R012-009CAS 183613-77-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.