Impurity or related compound · Ribavirin family
Pharmaceutical analytical standardRibavirin Impurity 26
Synonyms: Methyl 3-(1H-1,2,4-triazole-5-carbonylamino)-1H-1,2,4-triazole-5-carboxylate
- Cat. No.
- P-R048-059
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C7H7N7O3
- Molecular weight
- 237.18 g/mol
- Category
- Impurity or related compound
Family: Ribavirin
A synthetic guanosine analogue antiviral, synthesised in the early 1970s and approved for medical use in 1986: it is used for hepatitis C, combined with other drugs, and for some viral haemorrhagic fevers such as Lassa fever.
Did you know?One of its mechanisms is surprising: once built into the virus's RNA it multiplies copying errors, pushing the virus towards an 'error catastrophe' that leaves it unable to replicate.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
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Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
