Pharmacopoeial impurityRifampicin EP Impurity ACat. No. P-R053-002CAS 13983-13-6
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Active ingredient · Rifampicin family
Pharmaceutical analytical standardRifampicin
Synonyms: Rifampin, Rifaldazine, Rifamycin AMP, Rifaprodin, Rifoldin, Rifa, Riforal, Abrifam, Eremfat, Rifaldin, Rifoldine, R/AMP, Rifapiam, NSC 113926, Rifomycin SV, 8-(N-(4-methyl-1-piperazinyl)formidoyl)-, Rifadin Iv, Rifadin IV NOVAPLUS, Rifadin, Rimactane, Rimactan, Tubocin, Archidyn, Rifadine, Rimactizid, Rifagen, Rimazid, Arficin, Benemicin, Doloresum, Fenampicin, Rifaldazin, Rifamor, Rifobac, Sinerdol, Arzide, Rifcin, Rifam, Rifinah, Rimactazid, Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-, Rifamcin, Rifamsolin, Famcin, R-Cin, Rifater component rifampin, Rifamate component rifampin
- Cat. No.
- P-R053-001
- CAS
- 13292-46-1
- Alternative CAS
- 38776-75-9 (sodium salt)
- Formula
- C43H58N4O12
- Molecular weight
- 822.95 g/mol
- Category
- Active ingredient (API)
A semi-synthetic antibiotic of the rifamycin family, obtained in Milan in 1965 and first marketed in Italy in 1968: it is a cornerstone of tuberculosis treatment and is also used against leprosy.
Did you know?The rifamycins are named after the French film Rififi (1955), a favourite of the researchers who discovered them in 1957 in a bacterium from a soil sample on the French Riviera.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Rifampicin CRSEP R0700000
More products in the Rifampicin family
Pharmacopoeial impurityRifampicin EP Impurity ACat. No. P-R053-002CAS 13983-13-6
Pharmacopoeial impurityRifampicin EP Impurity BCat. No. P-R053-003CAS 125833-03-6
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Isotopically labelled25-Desacetyl Rifampicin-d4Cat. No. P-R053-005
Isotopically labelledRifampicin-13C-d3Cat. No. P-R053-006
Isotopically labelledRifampicin-d4Cat. No. P-R053-007
Impurity25-Deacetyl 27-Demethyl RifampicinCat. No. P-R053-008
Impurity25-Deacetyl-21-Acetyl RifampicinCat. No. P-R053-009CAS 1416773-22-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.