Active ingredientRisedronate Sodium 2.5 HydrateCat. No. P-R067-001CAS 329003-65-8
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Pharmacopoeial impurity · Risedronate family
Pharmaceutical analytical standardRisedronate EP Impurity E
Synonyms: Deoxy risedronic acid, Phosphonic acid, P,P'-(2-(3-pyridinyl)ethylidene)bis-
- Cat. No.
- P-R067-006
- CAS
- 75755-10-1
- Alternative CAS
- N/A
- Formula
- C7H11NO6P2
- Molecular weight
- 267.11 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Risedronate
A nitrogen-containing bisphosphonate with a pyridine group that slows bone resorption; approved in the United States in 1998 for Paget's disease and in 2000 for osteoporosis.
Did you know?Bisphosphonates mimic natural pyrophosphate, but with a P-C-P bridge that enzymes cannot break: known since 1865, before becoming medicines they were used in industry to prevent limescale deposits.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Risedronate impurity E CRSEP Y0001540
More products in the Risedronate family
Active ingredientRisedronate Sodium 2.5 HydrateCat. No. P-R067-001CAS 329003-65-8
Pharmacopoeial impurityRisedronate EP Impurity ACat. No. P-R067-002CAS 1486466-30-1
Pharmacopoeial impurityRisedronate EP Impurity BCat. No. P-R067-003CAS 105462-23-5
Pharmacopoeial impurityRisedronate EP Impurity CCat. No. P-R067-004CAS 105462-25-7
Pharmacopoeial impurityRisedronate EP Impurity DCat. No. P-R067-005CAS 501-81-5
Isotopically labelledRisedronic Acid-d4Cat. No. P-R067-007CAS 1035438-80-2
ImpurityRisedronate Related Compound A HydrateCat. No. P-R067-010CAS 1220806-40-5
ImpurityRisedronate Related Compound BCat. No. P-R067-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.