Active ingredientRizatriptan BenzoateCat. No. P-R074-001CAS 145202-66-0
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Pharmacopoeial impurity · Rizatriptan family
Pharmaceutical analytical standardRizatriptan EP Impurity H
Synonyms: Rizatriptan N-Oxide, N,N-Dimethyl-2-(5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl)ethanamine N-oxide, Rizatriptan benzoate impurity h (ep impurity), Rizatriptan benzoate impurity H, Rizatriptan N10-Oxide
- Cat. No.
- P-R074-011
- CAS
- 260435-42-5
- Alternative CAS
- N/A
- Formula
- C15H19N5O
- Molecular weight
- 285.35 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Rizatriptan
A triptan, a selective agonist of the serotonin 5-HT1B and 5-HT1D receptors, approved in the United States in June 1998 for the acute treatment of migraine attacks, with or without aura.
Did you know?It was the fourth triptan approved in the United States; it also comes as freeze-dried tablets that dissolve on the tongue within seconds, with no need for water.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Rizatriptan family
Active ingredientRizatriptan BenzoateCat. No. P-R074-001CAS 145202-66-0
Pharmacopoeial impurityRizatriptan EP Impurity ACat. No. P-R074-002CAS 887001-08-3
Pharmacopoeial impurityRizatriptan EP Impurity A BenzoateCat. No. P-R074-003CAS 1016900-25-6
Pharmacopoeial impurityRizatriptan EP Impurity B ChlorideCat. No. P-R074-004
Pharmacopoeial impurityRizatriptan EP Impurity CCat. No. P-R074-005CAS 208941-96-2
Pharmacopoeial impurityRizatriptan EP Impurity D ChlorideCat. No. P-R074-006
Pharmacopoeial impurityRizatriptan EP Impurity ECat. No. P-R074-008CAS 2757961-25-2
Pharmacopoeial impurityRizatriptan EP Impurity FCat. No. P-R074-009CAS 160194-39-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.