Active ingredientRotigotineCat. No. P-R089-001CAS 99755-59-6
Drag to rotate
Pharmacopoeial impurity · Rotigotine family
Pharmaceutical analytical standardRotigotine EP Impurity C
Synonyms: Despropylrotigotine
- Cat. No.
- P-R089-006
- CAS
- 153409-14-4
- Alternative CAS
- N/A
- Formula
- C16H19NOS
- Molecular weight
- 273.39 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Rotigotine
A non-ergoline dopamine agonist that stimulates dopamine receptors in the brain, given as a patch: approved in Europe in 2006 for Parkinson's disease, since 2008 it has also been used for restless legs syndrome.
Did you know?In 2007 it became the first Parkinson's treatment in patch form approved in the United States: through the skin, the drug is released steadily over 24 hours.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Rotigotine impurity C CRSEP Y0002016
More products in the Rotigotine family
Active ingredientRotigotineCat. No. P-R089-001CAS 99755-59-6
Active ingredientRotigotine HClCat. No. P-R089-002CAS 125572-93-2
Active ingredientRotigotine SulfateCat. No. P-R089-003CAS 128478-69-3
Pharmacopoeial impurityRotigotine EP Impurity BCat. No. P-R089-004CAS 78950-82-0
Pharmacopoeial impurityRotigotine EP Impurity B HClCat. No. P-R089-005CAS 1231158-77-2
Pharmacopoeial impurityRotigotine EP Impurity C HClCat. No. P-R089-007
Pharmacopoeial impurityRotigotine EP Impurity DCat. No. P-R089-008CAS 1369625-04-6
Pharmacopoeial impurityRotigotine EP Impurity ECat. No. P-R089-009CAS 2708278-87-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.