ImpurityTetrahydropalmatineCat. No. P-R090-002CAS 2934-97-6
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Active ingredient · Rotundine family
Pharmaceutical analytical standardRotundine
Synonyms: Gindarine, Hyndarine, Caseanine, Tetrahydropalmatine, l-, Tetrahydropalmatine, (-)-, Tetrahydropalmitine, l-Tetrahydropalmatine, Tetrahydropalmatine, dl-, Berbine, 2,3,9,10-tetramethoxy-, Hyndarin, O,O-Dimethyl-N-demethyl-cyclanoline, L-THP, Tetrahydropalmatine l-form
- Cat. No.
- P-R090-001
- CAS
- 483-14-7
- Alternative CAS
- 4880-82-4 (hydrochloride)
- 219697-24-2 (alternative CAS, same compound)
- Formula
- C21H25NO4
- Molecular weight
- 355.43 g/mol
- Category
- Active ingredient (API)
An isoquinoline alkaloid, the levorotatory form of tetrahydropalmatine, found in plants of the genus Corydalis, such as Corydalis yanhusuo, and in Stephania rotunda: in China it has been used as an analgesic and sedative.
Did you know?In 1940 the Vietnamese scientist Sang Dinh Bui extracted it from the root of Stephania rotunda and named it rotundine; only in 1965 was it shown to be the same molecule as tetrahydropalmatine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Rotundine family
ImpurityTetrahydropalmatineCat. No. P-R090-002CAS 2934-97-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.