Active ingredientSaxagliptinCat. No. P-S020-001CAS 361442-04-8
Drag to rotate
Active ingredient · Saxagliptin family
Pharmaceutical analytical standardSaxagliptin Monohydrate
Synonyms: Saxagliptin Hydrate, Onglyza, NSC 760407
- Cat. No.
- P-S020-003
- CAS
- 945667-22-1
- Alternative CAS
- 361442-04-8 (anhydrous form)
- 361442-05-9 (trifluoroacetate)
- 1370409-28-1 (hydrochloride hydrate)
- 1073057-20-1 (hydrochloride hydrate)
- 709031-78-7 (hydrochloride)
- Formula
- C18H25N3O2·H2O
- Molecular weight
- 333.43 g/mol
- Category
- Active ingredient (API)
Family: Saxagliptin
A DPP-4 inhibitor (gliptin) for type 2 diabetes, approved in 2009: it slows the breakdown of incretins, the gut hormones that boost insulin release after meals.
Did you know?Its structure contains an adamantane 'cage', a molecule whose name comes from the Greek adamantinos: its carbon atoms are arranged exactly as in a diamond crystal.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Saxagliptin impurity mixture CRSEP Y0002360
- Saxagliptin monohydrate CRSEP Y0002369
More products in the Saxagliptin family
Active ingredientSaxagliptinCat. No. P-S020-001CAS 361442-04-8
Active ingredientSaxagliptin HydrochlorideCat. No. P-S020-002CAS 709031-78-7
Pharmacopoeial impuritySaxagliptin USP Related Compound CCat. No. P-S020-004CAS 1350800-77-9
Isotopically labelled5-Hydroxy Saxagliptin-13C-d2 HClCat. No. P-S020-005
Isotopically labelledSaxagliptin-13C-d2 HClCat. No. P-S020-007
NitrosamineN-Nitroso Saxagliptin Cyclic Amidine ImpurityCat. No. P-S020-008
NitrosamineN-Nitroso Saxagliptin Impurity 1Cat. No. P-S020-009
NitrosamineN-Nitroso Saxagliptin Impurity 2Cat. No. P-S020-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.