Active ingredientSofosbuvirCat. No. P-S056-001CAS 1190307-88-0
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Impurity or related compound · Sofosbuvir family
Pharmaceutical analytical standardSofosbuvir Impurity 33
- Cat. No.
- P-S056-059
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C34H45FN4O13P2
- Molecular weight
- 798.69 g/mol
- Category
- Impurity or related compound
Family: Sofosbuvir
An antiviral that blocks the hepatitis C virus polymerase, approved in 2013. Combined with other antivirals it cures the infection in over 90% of patients in about three months.
Did you know?It turned hepatitis C, once treated with months of interferon and many side effects, into a disease cured with tablets.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Sofosbuvir family
Active ingredientSofosbuvirCat. No. P-S056-001CAS 1190307-88-0
MetaboliteSofosbuvir Metabolite GS566500Cat. No. P-S056-002CAS 1233335-78-8
Isotopically labelledSofosbuvir Impurity 99-13C-d3Cat. No. P-S056-004
Isotopically labelledSofosbuvir Nucleoside Derivative-13C-d3Cat. No. P-S056-008CAS 1256490-42-2
Isotopically labelledSofosbuvir-13C-d3Cat. No. P-S056-009CAS 2070009-25-3
Isotopically labelledSofosbuvir-d6Cat. No. P-S056-010CAS 1868135-06-1
Impurity(R)-Glyceraldehyde AcetonideCat. No. P-S056-011CAS 15186-48-8
ImpuritySofosbuvir Impurity 1Cat. No. P-S056-012CAS 23643-36-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.