Active ingredientSugammadexCat. No. P-S094-001CAS 343306-71-8
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Impurity or related compound · Sugammadex family
Pharmaceutical analytical standardSugammadex Diastereomer 2 Sulfoxide (Sodium salt)
Synonyms: Sugammadex Impurity 68 8*Sodium Salt
- Cat. No.
- P-S094-039
- CAS
- 2412953-14-9
- Alternative CAS
- 2412953-12-7 (free acid)
- Formula
- C72H104Na8O49S8
- Molecular weight
- 2194.03 g/mol
- Category
- Impurity or related compound
Family: Sugammadex
A modified gamma-cyclodextrin that traps the muscle relaxant rocuronium, and to a lesser extent vecuronium, quickly reversing its effect after anaesthesia: discovered in Scotland, it was approved in Europe in 2008 and in the United States in 2015.
Did you know?Its name describes its structure: 'su' stands for sugar and 'gammadex' for gamma-cyclodextrin, a ring of eight glucose units that wraps around the drug like a doughnut.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Sugammadex family
Active ingredientSugammadexCat. No. P-S094-001CAS 343306-71-8
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Impurity2-ThietanoneCat. No. P-S094-004CAS 2935-95-7
Impurity3,3'-Dithiodipropionic acidCat. No. P-S094-005CAS 1119-62-6
ImpuritySugammadex Impurity 1Cat. No. P-S094-006CAS 1378831-29-8
Impurity3-Mercaptopropionic AcidCat. No. P-S094-007CAS 107-96-0
ImpurityHexakis(6-bromo-6-deoxy)-alpha-cyclodextrinCat. No. P-S094-008CAS 53784-82-0
ImpuritySugammadex Impurity 2Cat. No. P-S094-009CAS 173094-60-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.