Active ingredientSuzetrigineCat. No. P-S142-001CAS 2649467-58-1
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Impurity or related compound · Suzetrigine family
Pharmaceutical analytical standardSuzetrigine Diastereomer (2S,3S,4R,5R)
- Cat. No.
- P-S142-020
- CAS
- 2649472-30-8
- Alternative CAS
- N/A
- Formula
- C21H20F5N3O4
- Molecular weight
- 473.40 g/mol
- Category
- Impurity or related compound
Family: Suzetrigine
A non-opioid painkiller that selectively blocks the NaV1.8 sodium channel, approved in the United States in January 2025 for moderate to severe acute pain in adults, the first of a new class.
Did you know?The NaV1.8 channel is found mainly in the peripheral neurons that sense pain, not in the brain: the medicine stops the signal before it reaches the central nervous system.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Suzetrigine family
Active ingredientSuzetrigineCat. No. P-S142-001CAS 2649467-58-1
Isotopically labelledSuzetrigine 13C-D3Cat. No. P-S142-002
Impurity(2S,3S,4S,5R) Suzetrigine DiastereomerCat. No. P-S142-003CAS 2649467-63-8
Impurity2-(3,4-Difluoro-2-methoxyphenyl)acetic acidCat. No. P-S142-004CAS 1558274-26-2
Impurity2-(4-Fluoro-2-methoxyphenyl)acetic acidCat. No. P-S142-005CAS 886498-61-9
ImpurityMethyl 4-aminopyridine-2-carboxylateCat. No. P-S142-006CAS 71469-93-7
ImpuritySuzetrigine 4-Desfluoro ImpurityCat. No. P-S142-007CAS 2879214-09-0
ImpuritySuzetrigine Diastereomer (2R,3S,4R,5R)Cat. No. P-S142-009CAS 2649467-65-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.