Active ingredientTamoxifen CitrateCat. No. P-T012-001CAS 54965-24-1
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Pharmacopoeial impurity · Tamoxifen family
Pharmaceutical analytical standardTamoxifen EP Impurity B
Synonyms: 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutan-1-ol, alpha-(4-(2-(Dimethylamino)ethoxy)phenyl)-beta-ethyl-alpha-phenylbenzeneethanol, alpha-(4-(2-(Dimethylamino)ethoxy)phenyl)-beta-ethyl-alpha-phenylphenethyl alcohol, Hydrated tamoxifen, Benzeneethanol, alpha-(4-(2-(dimethylamino)ethoxy)phenyl)-beta-ethyl-alpha-phenyl-
- Cat. No.
- P-T012-006
- CAS
- 748-97-0
- Alternative CAS
- N/A
- Formula
- C26H31NO2
- Molecular weight
- 389.54 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Tamoxifen
A selective oestrogen receptor modulator (SERM), synthesised in England in 1962 by chemist Dora Richardson: first marketed in the UK in 1973, it is a cornerstone of breast cancer treatment.
Did you know?It was born in a project for a contraceptive pill, but early studies showed it stimulated ovulation instead of suppressing it. In 1998 it became the first FDA-approved medicine to reduce the risk of breast cancer.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tamoxifen family
Active ingredientTamoxifen CitrateCat. No. P-T012-001CAS 54965-24-1
Pharmacopoeial impurityTamoxifen Citrate EP Impurity ACat. No. P-T012-002CAS 13002-65-8
Pharmacopoeial impurityTamoxifen Citrate EP Impurity A HydrochlorideCat. No. P-T012-003CAS 66584-36-9
Pharmacopoeial impurityTamoxifen Citrate EP Impurity D (as Z-Isomer)Cat. No. P-T012-004CAS 15917-50-7
Pharmacopoeial impurityTamoxifen Citrate EP Impurity F HydrochlorideCat. No. P-T012-005CAS 15917-65-4
Pharmacopoeial impurityTamoxifen EP Impurity CCat. No. P-T012-007CAS 19957-51-8
Pharmacopoeial impurityTamoxifen EP Impurity C (as E-Isomer)Cat. No. P-T012-008CAS 97151-10-5
Pharmacopoeial impurityTamoxifen EP Impurity D (E-Isomer)Cat. No. P-T012-009CAS 31750-45-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.