Active ingredientTazaroteneCat. No. P-T023-001CAS 118292-40-3
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Impurity or related compound · Tazarotene family
Pharmaceutical analytical standardTazarotene Impurity 3
Synonyms: Ethyl 6-[(Z)-2-chloro-2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethenyl]pyridine-3-carboxylate
- Cat. No.
- P-T023-010
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C21H22ClNO2S
- Molecular weight
- 387.92 g/mol
- Category
- Impurity or related compound
Family: Tazarotene
A third-generation acetylenic topical retinoid, a prodrug that becomes tazarotenic acid in the skin; approved in 1997, it is used for plaque psoriasis and acne.
Did you know?It was the first 'receptor-selective' topical retinoid for psoriasis: instead of activating all retinoic acid receptors, it acts mainly on RAR-beta and RAR-gamma.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tazarotene family
Active ingredientTazaroteneCat. No. P-T023-001CAS 118292-40-3
Isotopically labelledTazarotene-d6Cat. No. P-T023-002CAS 1246815-76-8
Isotopically labelledTazarotenic Acid-d6Cat. No. P-T023-003CAS 1794760-38-5
Impurity6-bromo-4,4-dimethylthiochromanCat. No. P-T023-004CAS 112110-44-8
Impurity6-Ethynyl-4,4-dimethylthiochromanCat. No. P-T023-005CAS 118292-06-1
ImpurityEthyl 4-chlorobenzoateCat. No. P-T023-006CAS 7335-27-5
ImpurityTazarotene Impurity 1Cat. No. P-T023-007
ImpurityTazarotene Impurity 2Cat. No. P-T023-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.