Active ingredientTazobactamCat. No. P-T025-001CAS 89786-04-9
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Active ingredient · Tazobactam family
Pharmaceutical analytical standardTazobactam Sodium Salt
Synonyms: Tazobactum, Tazobactum sodium, Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 4,4-dioxide
- Cat. No.
- P-T025-002
- CAS
- 89785-84-2
- Alternative CAS
- 89786-04-9 (free acid)
- Formula
- C10H11N4NaO5S
- Molecular weight
- 322.27 g/mol
- Category
- Active ingredient (API)
Family: Tazobactam
An inhibitor of beta-lactamases, the enzymes bacteria use to destroy penicillins and cephalosporins. Patented in 1982 and in use since 1992, it is paired with piperacillin and ceftolozane to protect them and broaden their spectrum.
Did you know?On its own it has very little antibacterial activity: it acts as a 'bodyguard', binding irreversibly to bacterial enzymes and disabling them before they can attack the antibiotic.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tazobactam family
Active ingredientTazobactamCat. No. P-T025-001CAS 89786-04-9
Pharmacopoeial impurityTazobactam USP Related Compound ACat. No. P-T025-003CAS 120701-87-3
Isotopically labelledTazobactam Impurity 32-d4Cat. No. P-T025-004
Isotopically labelledTazobactam Impurity 33-d4Cat. No. P-T025-005
Impurity1H-1,2,3-TriazoleCat. No. P-T025-007CAS 288-36-8
Impurity2-Benzhydryl-3-methylphenolCat. No. P-T025-008CAS 2234872-71-8
Impurity2-Benzhydryl-5-methylphenolCat. No. P-T025-009CAS 411239-19-5
ImpurityTazobactam Impurity 1Cat. No. P-T025-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.