Pharmacopoeial impurityTelmisartan EP Impurity BCat. No. P-T040-003CAS 1026353-20-7
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Active ingredient · Telmisartan family
Pharmaceutical analytical standardTelmisartan
Synonyms: Micardis, Pritor, Kinzalmono, Semintra, Tolura, Kinzal, Tazlok, Kinzal/Pritor, Telmisartar, Telmisatran, Telsite, Telday, Pharmakon1600-01505261, NSC 759811
- Cat. No.
- P-T040-001
- CAS
- 144701-48-4
- Alternative CAS
- 515815-48-2 (hydrochloride)
- 515815-47-1 (sodium salt)
- Formula
- C33H30N4O2
- Molecular weight
- 514.63 g/mol
- Category
- Active ingredient (API)
An angiotensin II AT1 receptor blocker (sartan) that relaxes blood vessels and lowers blood pressure. Patented in 1991 and in use since the late 1990s, it is used for hypertension and to reduce cardiovascular risk.
Did you know?It has the longest half-life of the sartans, about 24 hours, and also partially activates PPAR-gamma, the same receptor targeted by the glitazones used in diabetes.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- TelmisartanBP 1202
- Telmisartan CRSEP Y0000648
- Telmisartan for peak identification CRSEP Y0000649
- Telmisartan for system suitability CRSEP Y0001003
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MetaboliteTelmisartan Acyl GlucuronideCat. No. P-T040-010CAS 250780-40-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.