Active ingredientThiocolchicosideCat. No. P-T091-001CAS 602-41-5
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Pharmacopoeial impurity · Thiocolchicoside family
Pharmaceutical analytical standardThiocolchicoside EP Impurity C
Synonyms: 3-O-Demethylthiocolchicine, 3-Demethylthiocolchicine, NSC 361792, Acetamide, N-((7S)-5,6,7,9-tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, Thiocolchicoside Impurity 1, Acetamide, N-(5,6,7,9-tetrahydro-1,2-dimethoxy-3-hydroxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, (S)-
- Cat. No.
- P-T091-002
- CAS
- 87424-25-7
- Alternative CAS
- N/A
- Formula
- C21H23NO5S
- Molecular weight
- 401.48 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Thiocolchicoside
A semi-synthetic muscle relaxant with anti-inflammatory and analgesic action, used in short courses for painful muscle spasms, especially in low back pain, stiff neck and post-traumatic pain.
Did you know?It derives from colchicoside, a natural glucoside found in the autumn crocus (Colchicum autumnale), in which an oxygen atom is replaced by a sulphur atom: hence the prefix 'thio-'.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Thiocolchicoside family
Active ingredientThiocolchicosideCat. No. P-T091-001CAS 602-41-5
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Pharmacopoeial impurityThiocolchicoside EP Impurity HCat. No. P-T091-004
Pharmacopoeial impurityThiocolchicoside EP Impurity J (Mixture of Diastereomers)Cat. No. P-T091-005CAS 1359973-79-7
Pharmacopoeial impurityThiocolchicoside EP Impurity LCat. No. P-T091-007
Isotopically labelledThiocolchicoside-13C-d3Cat. No. P-T091-008
ImpurityThiocolchicoside Impurity D1SO2Cat. No. P-T091-009CAS 1359973-80-0
ImpurityThiocolchicoside TetraacetateCat. No. P-T091-010CAS 163956-01-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.