Active ingredientThioctic AcidCat. No. P-T092-001CAS 1077-28-7
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Impurity or related compound · Thioctic Acid family
Pharmaceutical analytical standardThioctic Acid Impurity 35
Synonyms: 5-[10,13-Bis(4-carboxybutyl)-1,2,6,7,11,12-hexathiacyclopentadec-3-yl]pentanoic acid
- Cat. No.
- P-T092-064
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C24H42O6S6
- Molecular weight
- 618.95 g/mol
- Category
- Impurity or related compound
Family: Thioctic Acid
Also known as alpha-lipoic acid, it is a small molecule with two sulphur atoms that acts as a cofactor for the mitochondrial enzymes that process pyruvate and alpha-ketoglutarate, key steps in extracting energy from food; in Germany it has been approved for diabetic neuropathy since 1966.
Did you know?To isolate its first crystals, in 1951, Lester Reed and colleagues processed about 10 tonnes of liver residue and obtained just 30 milligrams of pure substance.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Thioctic Acid family
Active ingredientThioctic AcidCat. No. P-T092-001CAS 1077-28-7
Pharmacopoeial impurityThioctic Acid EP Impurity ACat. No. P-T092-002CAS 1204245-29-3
Pharmacopoeial impurityThioctic Acid EP Impurity BCat. No. P-T092-003
Isotopically labelled(R)-alpha-Thioctic Acid-d4Cat. No. P-T092-004
Isotopically labelledrac-Thioctic Acid-d5Cat. No. P-T092-005CAS 1189471-66-6
Impurity(R)-6,8-dimercaptooctanoic acidCat. No. P-T092-006CAS 119365-69-4
Impurity(R)-Thioctic AcidCat. No. P-T092-007CAS 1200-22-2
Impurity(R)-Thioctic Acid TromethamineCat. No. P-T092-008CAS 137314-40-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.