Pharmacopoeial impurityThiopental EP Impurity ACat. No. P-T094-002CAS 29639-67-6
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Impurity or related compound · Thiopental family
Pharmaceutical analytical standardThiopental For Id And Assay
Synonyms: 5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione, Thiopental, Pentothiobarbital, Thiomebumal, Thiopentone, Thiopentobarbital, Penthiobarbital, Thionembutal, Thiopentobarbitone, Thiopentobarbituric acid, Thiothal, Tiopentale, Thiopental ciii, Trapanal, Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-, Thiopental (1mg/ml in Acetonitrile), Thiopental CIII (250 mg), Thiopental, 1mg/ml in Methanol, Thiopental for system suitability CRS, Pyrimidine, 5-ethyl-5,6-dihydro-4-hydroxy-2-mercapto-5-(1-methylbutyl)-6-oxo-
- Cat. No.
- P-T094-004
- CAS
- 76-75-5
- Alternative CAS
- 71-73-8 (sodium salt)
- Formula
- C11H18N2O2S
- Molecular weight
- 242.34 g/mol
- Category
- Impurity or related compound
Family: Thiopental
An ultra-short-acting barbiturate discovered in the early 1930s by American chemists Ernest Volwiler and Donalee Tabern: for decades it was one of the most widely used drugs for inducing general anaesthesia.
Did you know?It was first used in humans on 8 March 1934 by anaesthetist Ralph Waters: it puts the patient to sleep within 30 to 45 seconds.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Thiopental for id and assay CRSEP Y0002374
More products in the Thiopental family
Pharmacopoeial impurityThiopental EP Impurity ACat. No. P-T094-002CAS 29639-67-6
Pharmacopoeial impurityThiopental Sodium and Sodium Carbonate EP Impurity CCat. No. P-T094-003CAS 87171-21-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.