Active ingredientTopiramateCat. No. P-T162-001CAS 97240-79-4
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Impurity or related compound · Topiramate family
Pharmaceutical analytical standardTopiramate Dimer Impurity
- Cat. No.
- P-T162-015
- CAS
- 35405-70-0
- Alternative CAS
- N/A
- Formula
- C24H39NO13S
- Molecular weight
- 581.63 g/mol
- Category
- Impurity or related compound
Family: Topiramate
An antiepileptic discovered in 1979 by researchers Bruce Maryanoff and Joseph Gardocki and first approved as an anticonvulsant in 1996: it is used for several types of epileptic seizure and also to prevent migraine.
Did you know?It has an unusual structure for an antiepileptic, a fructose-like sugar carrying a sulfamate group: it was born in a diabetes project, and its anticonvulsant effect emerged by chance in early tests.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Topiramate family
Active ingredientTopiramateCat. No. P-T162-001CAS 97240-79-4
Pharmacopoeial impurityTopiramate EP Impurity ACat. No. P-T162-002CAS 20880-92-6
Pharmacopoeial impurityTopiramate EP Impurity BCat. No. P-T162-003CAS 876403-98-4
Pharmacopoeial impurityTopiramate EP Impurity CCat. No. P-T162-004CAS 106881-41-8
Pharmacopoeial impurityTopiramate EP Impurity DCat. No. P-T162-005CAS 950603-46-0
Isotopically labelledTopiramate-d12Cat. No. P-T162-006CAS 1279037-95-4
ImpurityTopiramate Impurity DCat. No. P-T162-007CAS 25018-67-1
Impurity2,3-Desisopropylidene TopiramateCat. No. P-T162-008CAS 851957-35-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.