Pharmacopoeial impurityTrandolapril EP Impurity CCat. No. P-T175-002
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Active ingredient · Trandolapril family
Pharmaceutical analytical standardTrandolapril
Synonyms: Mavik, Gopten, Odrik, Udrik, NSC 758939, Preran, Odric
- Cat. No.
- P-T175-001
- CAS
- 87679-37-6
- Alternative CAS
- 87725-72-2 (hydrochloride)
- Formula
- C24H34N2O5
- Molecular weight
- 430.55 g/mol
- Category
- Active ingredient (API)
An ACE inhibitor for high blood pressure, patented in 1981 and in use since 1993: it is a prodrug that the body converts into its active form, trandolaprilat, which lasts longer than other drugs in its class.
Did you know?It is almost a twin of ramipril: its two-ring core contains a six-carbon ring, a cyclohexane, where ramipril has a five-carbon one, a cyclopentane.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- TrandolaprilBP 1089
- Trandolapril CRSEP Y0000501
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Pharmacopoeial impurityTrandolapril EP Impurity CCat. No. P-T175-002
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Pharmacopoeial impurityTrandolapril EP Impurity BCat. No. P-T175-005
Pharmacopoeial impurityTrandolapril EP Impurity C HydrochlorideCat. No. P-T175-006
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NitrosamineN-Nitroso TrandolaprilCat. No. P-T175-008CAS 1026154-51-7
ImpurityTrandolapril Impurity 1Cat. No. P-T175-009CAS 760916-37-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.